Research Interests

• Genomic dynamics, epidemiological dynamics, and ecology of influenza A viruses
• Host-pathogen interaction of influenza A virus, especially host-immune responses of influenza infection and influenza cell tropisms
• Dynamics of microbial community in hosts/environments
• New pathogen discovery

Current Research Projects
NSF EPSCoR, Wan, P.I. Glycan profiles in dogs determining host specificity of canine influenza A virus.

NSF BCS, Emch, P.I., Wan, Co-P.I., Moody, Co-P.I., The geography of avian influenza evolution: Spatio-temporal relationships between virus genes and human-environment factors.

Most Current Publications:
Carrel, M., M. Emch, R.T. Jobe, A. Moody, and X.-F. Wan. 2010. Spatiotemporal structure of molecular evolution of H5N1 highly pathogenic avian influenza viruses in Vietnam. PLoS ONE, 5(1):e8631.

Jang, Y. and X.-F. Wan. 2010. Development of chemical bond based Elastic Network Model and its application in identifying functional motions in H5N1 highly pathogenic avian influenza viruses. International Journal of Bioinformatics Research and Applications, 6(1):1-11.

Luo, F., B. Li, X.-F. Wan, and R. H. Scheuermann. 2009. Core and periphery structures in protein interaction networks. BMC Bioinformatics, 10 (Suppl 4): S8.

Nguyen, T., C.T. Davis, W. Stembridge, B. Shu, A. Balish, K. Inui, H.T. Do, H.T. Ngo, X.-F. Wan, M. McCarron, S. E. Lindstrom, N. J. Cox, C.V. Nguyen, A. Klimov, and R. Donis. 2009. A novel highly pathogenic avian influenza H5N1 virus sublineage in poultry seized at ports of entry into Vietnam. Virology, 387:250-256.